A 46 gene panel that includes assessment of non-coding variants.

Ideal for patients who have any type of cholestasis including those with clinical suspicion of Alagille syndrome, citrullinemia type 2, Crigler-Najjar syndrome types 1 and 2, Dubin-Johnson syndrome, Gilbert syndrome, intrahepatic cholestasis of pregnancy type 3 or progressive familial intrahepatic cholestasis types 1-4.

Analysis methods Availability Number of genes Test code Retail Price
PCR 3 – 4 weeks 46 GHC 003 £ TBA

Detailed information

Androgenic alopecia is a form of polygenic inheritance with the presence of testosterone hormone, but it is also of clinical significance in women. It is dependent on the amount of androgen hormone on the androgen receptor (AR), but it is also influenced by genes that are located on chromosome X.

Alopecia predisposition genes located on chromosome X are inherited from maternal mothers. The increased risk of developing baldness is clinically significant also in polymorphisms on the 20th chromosome.

Who is the test suitable for?

Examination is appropriate if you experience excessive hair loss without apparent external causes, eg with some medication, long-term stress, hormonal changes - after delivery, etc.

What can this test reveal?

While in men this problem usually occurs between puberty and early adulthood, it is most common in menopausal women. The genetic test will help to confirm or rule out the assumptions about the disease or to reveal the cause of excessive hair loss.

How does the test work?

Genetic examination is performed from your DNA, which can be obtained by swabbing from the oral cavity (buccal wiping of the inside of your mouth cheek - DNA isolation from oral mucosal cells). You can take the sample yourself in the comfort of your home and send it to our lab, or have your collection taken by your GP.

How is the test done?

You can order the test from attending your Doctor/GP, private clinic or online at ghcgenetics. Once you have signed the informed consent form, either a swab of your mouth will be taken or a blood sample will be collected. Once the genetic analysis is finished, you or your Doctor/GP will receive a report with the results and based on these he/she will recommend suitable preventive measures.