|Analysis methods||Availability||Number of genes||Test code||Retail Price|
|PCR||3 – 4 weeks||GHC 021||£ TBA|
The TromboGen genetic test can help you find out if you have a congenital
predisposition for blood clotting. If you have an increased genetic risk, you will be
advised on appropriate treatment and preventive monitoring to prevent the above
complications. It is also important to follow general recommendations for the
prevention of thrombosis.
Did you know that your blood has a higher coagulation factor during pregnancy?
This is a normal physiological condition in all expectant mothers, which you don’t have to worry about. However, if you have a congenital predisposition for increased blood coagulation, you are at a higher risk of serious complications during pregnancy, childbirth and puerperium.
What complications does this involve?
miscarriage or premature birth
delayed growth of the foetus
cleft defects of the foetus’s spine and spinal cord
pre-eclampsia (increased blood pressure and renal failure)
venous thrombosis (blood clots) and subsequent embolism
(blood clot being released and blocking a blood vessel)
How does the test work?
Genetic examination is performed from your DNA, which can be obtained by swabbing from the oral cavity (buccal wiping of the inside of your mouth cheek - DNA isolation from oral mucosal cells). You can take the sample yourself in the comfort of your home and send it to our lab, or have your collection taken by your GP.
How is the test done?
Your gynaecologist will go over your personal and family medical history with you and based on this information he/she will determine whether the TromboGen® test will be reimbursed by your health insurance company or not. Once you have signed the informed consent form, either a swab of your mouth will be taken or a blood sample will be collected. Once the genetic analysis is finished, your physician will receive a report with the results and based on these he / she will recommend suitable preventive measures. If a mutation is uncovered, you will be referred for genetic consultation (there, it will be recommended that the rest of your family members undergo testing) and for a haematological exam.